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Technická 5
166 28 Prague 6 – Dejvice
IČO: 60461337
VAT: CZ60461373
Czech Post certified digital mail code: sp4j9ch
Copyright UCT Prague 2017
Informations provided by the Dean's Office. Technical support by the Computing Centre.
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[obsah] => Nobel Prize winner Vlado Prelog, versatile chemist Emil Votoček, inventor of soft contact lenses Otto Wichterle and many other prominent FCHT graduates helped enhance the fields of study taught at the faculty. At present, these fields embrace development of new (bio) materials with unique properties, alternative sources of energy preparation with (as yet) unknown substances and new medical drugs, and even methods for preserving national cultural heritage. We are training experts who shift the boundaries of knowledge while being aware of their responsibility for maintaining the fragile natural balance. As the classic has put it: "Cherchez chemie!" How true.
We offer studies in interesting and promising directions of advanced chemistry
- Biomaterials for medical purposes (metallic, ceramic and polymeric implants)
- Materials of special properties (nanomaterials, optical waveguides, superconductors)
- Catalysis, reactor engineering, modeling and informatics in chemistry
- Drugs synthesis and manufacturing
- Pharmaceuticals, fragrances, chemical specialties
- Glass, ceramics; crystals; plastics, rubbers
- Conservation and restoration of historical monuments (metallic, wooden and stone)
Research and Development
Research and development activities in the faculty are oriented around basic and applied research in chemistry, chemical technology, and the chemistry of materials (metallic, inorganic non-metallic, polymeric and composite). The faculty is important partner for the chemical and materials industries in both the Czech Republic and abroad.
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We offer advanced studies into interesting and promising directions of advanced chemistry
- Biomaterials for medical purposes (metallic, ceramic, and polymeric implants)
- Materials of special properties (nanomaterials, optical waveguides, superconductors)
- Catalysis, reactor engineering, modeling and informatics in chemistry
- Drugs synthesis and manufacturing
- Pharmaceuticals, fragrances, chemical specialties
- Glass, ceramics; crystals; plastics, rubbers
- Conservation and restoration of historical monuments (metallic, wooden and stone)
Research and Development
Research and development activities in the faculty are oriented towards basic and applied research in chemistry, chemical technology, and the chemistry of materials (metallic, inorganic non-metallic, polymeric and composite). The faculty is an important partner forchemical and materials industries both in the Czech Republic and abroad.
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Chemistry and Technology of Materials
- Development of new metals, polymers, and ceramic materials
- Biomaterials for medicinal use
- Corrosion
- Composite materials
- Superconductors and materials for optoelectronics
- Microanalytical methods and methods of analysis of structural and phase analysis of materials
- Physical chemistry methods for solid materials surface modification
- Chemical stability of materials of monuments
- Solving problems in the polymorphism of substances.
Chemistry and Chemical Technology
- Design and optimization of chemical and electrochemical reactors
- Kinetics of catalyzed and non-catalyzed reactions
- Preparation and characterization of novel catalysts
- Modelling and simulation of chemical processes
- Chemical processes waste treatment
- Fine chemicals
- Chemical and electrochemical synthesis of novel compounds
- Development, optimization and theoretical study of pharmaceutical processes
The faculty offers expert consultation and development work in all of the above areas. Individual departmental pages contain more detailed information about research activities.
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Institute of Chemical Process Fundamentals of the CAS, v.v.i.
Catalysts for the oxidation of volatile organic compounds
| Granting Departments: |
Department of Organic Technology
Institute of Chemical Process Fundamentals of the CAS, v.v.i. |
| Study Programme/Specialization: | Chemistry and Chemical Technologies ( in English language ) |
| Supervisor: | Ing. Pavel Topka, Ph.D. |
Annotation
Volatile organic compounds (VOC) are one of the main contributors to air pollution. They are precursors of photochemical smog (ground-level ozone) and very efficient greenhouse gases (up to 11 times more effective compared to CO2). Furthermore, they are detrimental not only to the environment but also to the human health due to their harmful properties (toxic, malodorous, mutagenic and carcinogenic). Therefore, increasingly strict regulations are being put in place worldwide in order to reduce VOC emissions into the atmosphere. VOCs are emitted from thousands of different sources like chemical plants, petroleum refineries, power plants, paint industry, gas stations, dry cleaners etc. In the industry, the old thermal incineration units are retrofitted with the catalytic oxidation technology, which is a green and cost-effective method for the abatement of VOC emissions. The aim of the thesis is the development of new catalysts for VOC oxidation. The activity and selectivity of the prepared catalysts in the oxidation of model VOCs will be correlated with their physicochemical properties in order to identify the factors important for their efficiency. Required education and skills: • master degree in chemical engineering, physical chemistry, organic technology, chemical physics or similar; • willingness to do experimental work and learn new things, team work ability.
Contact supervisor
Study place:
Institute of Chemical Process Fundamentals of the CAS, v.v.i.
Catalysts of heteroatom elimination in the refining of hydrocarbon feeds
| Granting Departments: |
Department of Organic Technology
Institute of Chemical Process Fundamentals of the CAS, v.v.i. |
| Study Programme/Specialization: | Chemistry and Chemical Technologies ( in English language ) |
| Supervisor: | Mgr. Luděk Kaluža, Ph.D. |
Annotation
Heteroatoms N, O, S, or Cl bound in hydrocarbons represent a barrier in the chemical processing of fossil and renewable feeds, because they are a source of corrosion in chemical equipment, catalytic poisons, harm the environment or deteriorate the energy value of hydrocarbons. These heteroatoms are therefore removed by decomposition reactions to form hydrogenated heteroatoms and pure hydrocarbons. Some decompositions are accompanied by C-C condensation reactions (Guerbet coupling, aldol condensation). The study will cover the synthesis of new heterogeneous catalysts including the evaluation of their activity and selectivity in model reactions performed in laboratory tubular flow microreactors. Gas and liquid chromatography (GC/FID/MSD/SCD, LC/qTOF) creates the chemical-analytical background for the reaction progress kinetic analysis (RPKA). Microstructural characterization of the prepared catalysts will comprise N2/Ar physisorption, inverse chromatography, XRD, XPS, Raman/IR spectroscopy or SEM/HR-TEM microscopy.Required education and skills • Master degree in chemistry, chemical technology, chemical engineering; • experience with varied experimental work in a chemical laboratory; • ability to work as part of a team.
Contact supervisor
Study place:
Institute of Chemical Process Fundamentals of the CAS, v.v.i.
Electrodeless discharge lamps in the preparation of polyaromatics
| Granting Departments: |
Department of Organic Chemistry
Institute of Chemical Process Fundamentals of the CAS, v.v.i. |
| Study Programme/Specialization: | Chemistry and Chemical Technologies ( in English language ) |
| Supervisor: | Dr. Ing. Vladimír Církva |
Annotation
Proposal is based on the connection of two scientific disciplines: traditional photochemistry and recently developed microwave chemistry, when the effect of UV/Vis and microwave radiation on the chemical and physical properties of molecules is studied. The required radiation is generated completely atypically directly by the microwave field using so-called electrodeless discharge lamps (EDLs). The aim of the project is basic research in the preparation of EDLs (mercury, sulfur, other metal) and optimization of the effect of microwave and UV/vis radiation on the photocyclization of stilbene derivatives, which can lead to polyaromatics. Required education and skills: • master degree in organic technology or organic chemistry, • experimental skill and practical knowledge of reaction optimization, • team work ability, • employment contract at ICPF.
Contact supervisor
Study place:
Institute of Chemical Process Fundamentals of the CAS, v.v.i.
Microwave photochemistry and preparation of polyaromatic compounds
| Granting Departments: |
Department of Organic Chemistry
Institute of Chemical Process Fundamentals of the CAS, v.v.i. |
| Study Programme/Specialization: | Chemistry ( in English language ) |
| Supervisor: | Dr. Ing. Vladimír Církva |
Annotation
Proposal is based on the connection of two scientific disciplines: traditional photochemistry and recently developed microwave chemistry, when the effect of UV/Vis and microwave radiation on the chemical and physical properties of molecules is studied. The required radiation is generated completely atypically directly by the microwave field using so-called electrodeless discharge lamps. The aim of the project is basic research and optimization into the influence of microwave radiation on the course of cis-trans photoisomerization and photocyclization of stilbene and o-terphenyl derivatives, leading to phenanthrene, triphenylene, phenacene, helicene analogues or their N- and S-hetero derivatives, which may find application in molecular electronics. Required education and skills: • master degree in organic technology, • experimental skill and practical knowledge of reaction optimization, • team work ability.
Contact supervisor
Study place:
Institute of Chemical Process Fundamentals of the CAS, v.v.i.
Modular synthesis of dendritic carriers of drugs for applications in regenerative medicine
| Granting Departments: |
Department of Organic Chemistry
Institute of Chemical Process Fundamentals of the CAS, v.v.i. |
| Study Programme/Specialization: | Drugs and Biomaterials ( in English language ) |
| Supervisor: | Ing. Tomáš Strašák, Ph.D. |
Annotation
The project is focused on the application of modular synthesis principles to a preparation of novel dendritic materials with properties tailored for medicinal applications, especially in the field of regenerative medicine. The first stage comprises the synthesis of a library of carbosilane building blocks (dendrons) using silicon atom as a branching point and bearing suitable peripheral functional groups (saccharide ligands, cationic groups, PEGyl chains etc.). These components will then be used for the construction of multifunctional macromolecular compounds with precisely defined dendritic structure. The application of prepared materials to the encapsulation of small molecule drugs, complexation of therapeutically active proteins and growth factors, and physically-chemical characterization of these systems will be an inherent part of the work, with emphasis on suitable pharmacokinetic and cytotoxic behavior. The work is a part of the research project supported from OP JAK fund; within this project the student will closely collaborate with external partners on the application of the prepared materials. Required education and skills • Master degree in organic chemistry, organic technology; • enthusiasm for experimental work and learning of new things; • team work ability.
Contact supervisor
Study place:
Institute of Chemical Process Fundamentals of the CAS, v.v.i.
Phosphorus heterocycles: the new frontier in redox flow battery technology
| Granting Departments: |
Department of Organic Chemistry
Institute of Chemical Process Fundamentals of the CAS, v.v.i. |
| Study Programme/Specialization: | Chemistry ( in English language ) |
| Supervisor: | Ing. Jan Storch, Ph.D. |
Annotation
The transition to a low-carbon economy requires renewable energy sources and increased energy storage capacity in stationary applications. Lithium-ion batteries, despite their recent advancements, are constrained by short-term storage capacity and energy loss over multiple cycles, diminishing their lifespan. They also present safety and reliability concerns. Organic radical flow batteries (ORFBs), using organic redox-active molecules instead of traditional metal compounds, offer an alternative. This project aims to develop phosphorus heterocycles for ORFBs, ensuring stability over a broad temperature range, and providing high energy density and cyclability. The goal is to surpass the limitations of existing quinone and phenazine-based electrolytes, matching the performance of commercially used vanadium-based ORFBs. Required education: • Master's degree in Organic/Inorganic Chemistry or Organic Technology and related fields.
Contact supervisor
Study place:
Institute of Chemical Process Fundamentals of the CAS, v.v.i.
Preparation of nanofibrous catalysts by electrospinning technique
| Granting Departments: |
Department of Organic Technology
Institute of Chemical Process Fundamentals of the CAS, v.v.i. |
| Study Programme/Specialization: | Chemistry and Chemical Technologies ( in English language ) |
| Supervisor: | Ing. Karel Soukup, Ph.D. |
Annotation
The main aim of the proposed project is focused on assessment of the specific properties of the novel polymeric nanofibrous materials prepared by electrospinning in applications as effective catalyst supports. Other targets of this project will be specifically addressed to the optimization of the electrospinning process parameters with respect to properties of the prepared supports, deposition of the catalytically active centers or catalyst precursors and assessment of the effect of support microstructure on the phenomenological kinetics of model reactions. Studied model reactions will involve both reaction in gas-phase (total oxidation of volatile organic compounds) and liquid-phase (selective hydrogenation of unsaturated carbonyl compounds). Additionally, it will be investigated the possible influence of differences between polymer surface nature of nanofibers and conventional polymeric catalyst supports on catalytic properties. Required education and skills: • Master degree in chemical technologies, chemical engineering or chemistry of materials; • methodical and creative approach to work; • willingness to perform experimental work and learn new issues.
Contact supervisor
Study place:
Institute of Chemical Process Fundamentals of the CAS, v.v.i.
Preparation of phospha-nanographenes
| Granting Departments: |
Department of Organic Chemistry
Institute of Chemical Process Fundamentals of the CAS, v.v.i. |
| Study Programme/Specialization: | Chemistry ( in English language ) |
| Supervisor: | Ing. Jan Storch, Ph.D. |
Annotation
π-Conjugated organophosphorus systems have become the subject of intensive research in recent years, primarily due to their applications in materials chemistry. The presence of the phosphorus atom in these molecules facilitates further derivatization, effectively altering some key characteristics of the target molecules and their intended applications. A special place in this class of substances is occupied by six-membered phosphacycles. Although considerable progress has been made recently in synthesizing these substances, polyaromatic compounds incorporating a phosphinine ring remain rare. This study will investigate synthetic routes for introducing the phosphinine core into nanographene structures. The properties of these novel compounds will also be extensively studied. Required education: • Master's degree in Organic/Inorganic Chemistry or Organic Technology and related fields.
Contact supervisor
Study place:
Institute of Chemical Process Fundamentals of the CAS, v.v.i.
Synthesis of glycomimetic organometallic inhibitors of galectins
| Granting Departments: |
Department of Organic Chemistry
Institute of Chemical Process Fundamentals of the CAS, v.v.i. |
| Study Programme/Specialization: | Chemistry ( in English language ) |
| Supervisor: | Mgr. Jindřich Karban, Ph.D. |
Annotation
Galectins are a class of lectins (carbohydrate-binding proteins other than enzymes and antibodies) characterized by affinity to some galactosides and sequence homology. Non-covalent interactions of galectins with oligosaccharides are involved in many fundamental biological events. Inhibition of these interactions by synthetic analogs of saccharides (glycomimetics) is of principal significance in their study as well as in drug development. The main goal of this PhD project is the synthesis and evaluation of hybrid glycomimetic galectin inhibitors based on the combination of carbohydrate and organometallic structural motifs. Installation of an organometallic moiety into the structure of a glycomimetic inhibitor can not only result in higher affinity or selectivity of inhibition, but also enable to study the interactions with galectins by means of electrochemical methods. Required education and skills • Master degree in chemistry. • The willingness to acquire and apply advanced methods of organic synthesis.
Contact supervisor
Study place:
Institute of Chemical Process Fundamentals of the CAS, v.v.i.
Synthesis of mono- and multivalent inhibitors of tandem galectins
| Granting Departments: |
Department of Organic Chemistry
Institute of Chemical Process Fundamentals of the CAS, v.v.i. |
| Study Programme/Specialization: | Chemistry ( in English language ) |
| Supervisor: | Mgr. Jindřich Karban, Ph.D. |
Annotation
Galectins are a class of lectins (carbohydrate-binding proteins other than enzymes and antibodies) characterized by affinity to galactosides and sequence homology. The so-called tandem galectins comprise two related but non-identical carbohydrate-binding domains (CRD) with a partially different substrate specificity. The inhibition of tandem galectins by synthetic analogs of saccharides (glycomimetics) is of principal significance in fundamental research as well as in drug development. Attachment of monovalent domain-specific inhibitors to suitable carriers will give rise to multivalent inhibitors that can inhibit both domains within the tandem galectin simultaneously and very effectively if the right topology is achieved. The main goal of this PhD project is the synthesis and evaluation of glycomimetic inhibitors of individual domains and verification of the hypothesis that an appropriate spatial arrangement of domain-specific inhibitors on a multivalent carrier can lead to high affinity inhibitors of tandem galectins due to a multivalent effect. Required education and skills • Master degree in chemistry. • The willingness to learn and apply advanced methods of organic synthesis.
Contact supervisor
Study place:
Institute of Chemical Process Fundamentals of the CAS, v.v.i.
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